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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM5
All Species:
28.79
Human Site:
Y224
Identified Species:
52.78
UniProt:
Q96HS1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HS1
NP_612642.1
289
32004
Y224
A
R
Q
E
E
D
S
Y
E
I
F
I
C
H
A
Chimpanzee
Pan troglodytes
XP_509498
465
51564
Y224
A
R
Q
E
E
D
S
Y
E
I
F
I
C
H
A
Rhesus Macaque
Macaca mulatta
XP_001083353
235
26735
F173
E
E
D
S
Y
E
I
F
I
C
H
A
N
V
I
Dog
Lupus familis
XP_543346
289
31978
Y224
V
K
Q
Q
E
D
S
Y
E
I
F
I
C
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX10
288
31976
Y223
A
R
Q
E
E
D
S
Y
E
I
F
I
C
H
A
Rat
Rattus norvegicus
Q562B5
288
32042
Y223
A
K
Q
E
E
D
S
Y
E
I
F
I
C
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510978
229
26244
F167
E
E
D
S
Y
E
I
F
I
C
H
A
N
V
I
Chicken
Gallus gallus
XP_415083
212
24106
F150
E
E
D
S
Y
E
I
F
V
C
H
A
N
V
I
Frog
Xenopus laevis
Q5FWM4
275
30968
Y210
P
K
Q
E
E
D
S
Y
E
I
L
I
C
H
A
Zebra Danio
Brachydanio rerio
Q502L2
289
32155
Y224
A
K
Q
K
E
D
S
Y
E
I
I
V
C
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46084
289
33147
Y215
P
D
Q
E
K
E
S
Y
T
L
I
V
G
H
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09422
284
32472
F219
P
S
Q
K
E
D
S
F
E
L
I
V
C
H
A
Sea Urchin
Strong. purpuratus
XP_793164
286
31924
F221
P
A
Q
T
E
N
S
F
E
V
I
V
C
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
79.9
93
N.A.
93.4
92.7
N.A.
70.9
64.3
65
64.7
N.A.
46
N.A.
42.5
53.6
Protein Similarity:
100
62.1
81.3
97.5
N.A.
96.1
96.8
N.A.
76.8
70.5
78.1
77.1
N.A.
61.9
N.A.
59.1
67.1
P-Site Identity:
100
100
0
80
N.A.
100
93.3
N.A.
0
0
80
73.3
N.A.
33.3
N.A.
53.3
46.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
13.3
13.3
86.6
93.3
N.A.
60
N.A.
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
0
0
0
0
0
0
0
0
0
24
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
24
0
0
70
0
0
% C
% Asp:
0
8
24
0
0
62
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
24
0
47
70
31
0
0
70
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
39
0
0
39
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
24
0
0
77
0
% H
% Ile:
0
0
0
0
0
0
24
0
16
54
31
47
0
0
24
% I
% Lys:
0
31
0
16
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
24
0
0
% N
% Pro:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
77
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
24
0
0
77
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
8
0
31
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _